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Dr. Kim Connelly is a Cardiologist and Scientist who is both nationally recognized as an expert in echocardiography, cardiovascular MRI and the impact of diabetes upon cardiac function and ventricular remodeling. His work has been recognized evident by winning the “Young Investigator of the Year Award” by the Canadian Cardiovascular Society, an Early Researcher Award in 2014, and a CIHR New Investigator award in 2014.
Dr. Connelly runs a basic research laboratory at the Keenan Research Centre at St. Michael’s Hospital where he focuses upon basic mechanisms of disease – primarily around the role of pathological extracellular matrix accumulation and the pro-sclerotic cytokine transforming growth factor beta, with a focus upon translating discoveries into therapies in humans. He developed the first hemodynamically validated model of diabetes induced HFpEF. He is the Director of the Krembil Stem Cell Facility at St. Michael’s Hospital and uses regenerative cell based therapies to improve cardiac and renal dysfunction as a result of diabetes. He has research support from the HSF of Canada, CIHR and CFI along with research support from the pharmaceutical industry. His work has been published in journals such as the NEJM, Circulation, Journal of the American college of Cardiology, Circulation Research, Diabetes, Cell Metabolism and Lancet Endocrinology and Diabetes. His H index is 41, and I index of 125.
Dr Connelly is immediate past president of the Canadian Society of Cardiac Magnetic resonance imaging. He runs a translational imaging laboratory and uses hyperpolarized C13 metabolic imaging to understand metabolism in the human heart in real time, as well as CMR to understand the impact of exercise upon cardiac remodeling. He was senior author of the EMPA HEART study along with Dr Verma and Zinman to assess the mechanism by which the SGLT2i empagliflozin provided cardiac protection in patients with type 2 DM. Finally, he was past section lead of 2018 macrovascular complications section for the Diabetes Canada Clinical practice updates and is current chair of the Canadian Cardiovascular Society guidelines.
Ildiko Lingvay
Southwestern Medical Center, Dallas, USA
Ildiko Lingvay is Professor in the Division of Endocrinology and the
Department of Population and Data Sciences at the University of Texas
(UT) Southwestern Medical Center in Dallas, TX, USA. She also serves
as Medical Director of the Office of Clinical Trials Management
overseeing the institutional review and approval of all clinical
studies and clinical trials at UT Southwestern. She sees patients at
the university clinics and hospital, as well as at the Parkland Health
System.
Dr Lingvay leads a clinical research
programme in the field of obesity, diabetes and associated metabolic
complications with the ultimate goal of improving the lives of all
patients who suffer from the many health consequences of these
conditions. Her research interests span the spectrum from
pathophysiology of the disease to comparative effectiveness of
therapeutic approaches. She has participated in many clinical trials
in the field and has a special interest in cardiovascular trials in
diabetes and obesity. She has published over 100 manuscripts in major
medical journals and has contributed to several diabetes textbooks.
She is an active member of the American Diabetes Association, where
she served on the Scientific Sessions Organizing Committee and
currently is on the grant review committee and a board member of the
WIN ADA and Focus on Fellows initiatives.
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Subodh Verma
St. Michael’s Hospital, Toronto, Canada
Dr Subodh Verma is an internationally renowned cardiac
surgeon-scientist and Professor at the University of Toronto. He is
the current Canada Research Chair in Cardiovascular Surgery, having
previously served as the Canada Research Chair in Atherosclerosis
(2007-2017). Dr Verma was recently awarded the 2021 Lister Prize in
Surgery from the University of Toronto in recognition of his
outstanding and continuing productivity of international stature. He
is a past recipient of the Howard Morgan Award for Distinguished
Achievements in Cardiovascular Research and the Royal College of
Physicians and Surgeons of Canada Gold Medal in Surgery. He is an
appointee of the American Association of Thoracic Surgeons (AATS) and
a member of the College of New Scholars, Artists and Scientists, Royal
Society of Canada. According to Google Scholar in April 2021, Dr Verma
has an hindex of 100 and his work has been cited over 50,000
times.
Dr Verma has published extensively in
highly impactful journals like the NEJM, Lancet, Circulation, JACC,
Nature, and JCI. He is an Associate Editor of the European Heart
Journal. Dr Verma is an active contributor to Canadian clinical
practice guidelines and co-authored the recently updated
recommendations for atrial fibrillation, antiplatelet therapy,
diabetes, and heart failure; he was a member of the 2018 AATS
consensus guidelines committee on bicuspid aortic valve-related
aortopathy. Dr Verma has served in various capacities on the American
Heart Association Councilon Cardiovascular Surgery and Anesthesia
since 2008.
Dr Verma had/has leadership roles on
10 contemporary global heart failure trials – several of which have
let to paradigm changes in how individuals all around the world who
live with diabetes and heart failure are now managed. He founded and
oversees the CardioLink platform at St Michael’s Hospital that is
conducting cardiometabolic and surgically oriented RCTs and
translational studies.
Dr Verma leads a dynamic pre-clinical and translational research team that leverages pre-clinical disease models and clinical trial-derived data to identify novel mediators of cardiovascular and cardiometabolic disease as well as answer timely and relevant healthcare questions. His research has yielded 2 United States patents and is supported by several national peer-reviewed grants.
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