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Speaker - alexander-augusto
Dr Reiko
Director of the Endocrinology and Metabolism Division of the Japanese National Centre for Child Health and Development (NCCHD), Tokyo, Japan.

Dr Horikawa, a paediatric endocrinologist, is the Director of the Endocrinology and Metabolism Division of the Japanese National Centre for Child Health and Development (NCCHD) and has been with the NCCHD since 2002. She is the author of over 300 original, peer-reviewed endocrinology articles (174 English/152 Japanese) and has contributed to 43 book publications. Dr Horikawa earned her M.D. from Tohoku University and completed her residency in paediatric endocrinology at the National Children’s Hospital, Tokyo, Japan. After her post-doctoral fellowship at the University of Virginia Health Sciences, she returned back as Faculty at the National Children’s Hospital, Department of Endocrinology and Metabolism. She has served in executive board member positions in several important national and international professional society groups such as Japan Endocrine Society, Asia Pacific Endocrine Society and Growth Hormone Research Society (GRS). She continues to be active in her editorial work and research interests (growth, sex development, and maturation, neuroendocrinology (hypothalamus-pituitary axis), adrenal disorders). In 2016, Dr Horikawa was awarded the Japanese Society of Pediatric Endocrinology Kenji Fujieda award


Alexander Augusto de Lima Jorge

University of São Paulo (USP), Associate Professor of Medicine at The University of Sao Paulo (USP), School of Medicine, São Paulo, Brazil.

Dr. Jorge is a principal investigator at the Genetic Endocrinology Unit. He is an expert in growth disorders and has published more than 180 papers in international scientific journals, with more than 3,600 citations (h-index of 34). He characterized several new genetic conditions associated with growth disorders, such as alterations involving the Natriuretic peptide system (NPPC and NPR2); Noonan syndrome associated with SOS2 or LZTR1 mutations, homozygous defects in BRCA1, and genetic syndrome associated with SCUBE3 and BCL11B mutations.


He is a member of the Endocrine Society, the European Society for Paediatric Endocrinology (ESPE), the Latin American Society of Pediatric Endocrinology (SLEP), and the Brazilian Endocrine Society (SBEM). Dr. Jorge is responsible for the molecular genetic investigation of endocrine-genetic disorders at the largest hospital in South America (Hospital das Clínicas). He is in charge of an outpatient clinic for children with growth disorders, with more than 600 children each year. The focus of our outpatient clinics is children with syndromic short and tall stature, patients with rare defects of the GH/IGFs axis, and cases of isolated short stature (ISS and SGA). His research is centered on discovering and understanding the genetic mechanisms involved in growth and development disorders. 


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