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Roxana Mehran, MD, is an internationally renowned clinical research expert in the field of interventional cardiovascular disease. She has built a globally respected academic research centre that is focused on developing randomised clinical trials, outcomes research projects and high-impact academic publications. She has served as principal investigator for numerous global studies, developed risk scores for bleeding and acute kidney injury, participates regularly in developing clinical guidelines, and has authored more than 1,300 peer-reviewed articles. Dr Mehran is a current member of the American College of Cardiology (ACC) Board of Trustees, and is a founder and was Chief Scientific Officer of the Cardiovascular Research Foundation (CRF). She has been included for the past four consecutive years in Clarivate Analytics: “Most Cited Researchers – Top 1%”, as well as “The World’s Most Influential Scientific Minds” (Thomson Reuters).
Dr Mehran is currently leading the The Lancet Commission on Women’s Cardiovascular Diseases, which brings together leading female researchers from around the world to identify and bridge gaps in research and care for women with cardiovascular disease. She was recently named Director of the Women’s Heart and Vascular Center at Mount Sinai Heart, spearheading a new programme that represents a collaboration across multiple disciplines and that is designed to meet the unique needs of women’s cardiovascular health. In 2019, she founded Women as One, which is dedicated to advancing opportunities for women in medicine.
Dr Mehran is a recipient of several awards, including the 2016 ACC Bernadine Healy Leadership in Cardiovascular Disease Award, the 2018 Nanette Wenger Award from WomenHeart for excellence in research and education, the 2019 Ellis Island Medal of Honor, and the 2019 European Society of Cardiology Silver Medal and Andreas Grüntzig Lecture Plaque. In 2022, she received more awards: the Terry Ann Krulwich Physician-Scientist Alumni Award, Mount Sinai; the Linda Joy Pollin Heart Health Leadership Award; Doctor Honoris Causa Degree at Università della Svizzera Italiana; Women in Cardiology Mentoring Award, American Heart Association; and the Pulse-Setter Champion Award, CRF.
Paul M. Ridker
Brigham and Women's Hospital, Boston, Massachusetts, USA
Paul M. Ridker serves as the Eugene Braunwald Professor of Medicine at the Harvard Medical School and as Director of the Center for Cardiovascular Disease Prevention at Brigham and Women’s Hospital in Boston, Massachusetts, USA. Over a 30-year period, Dr Ridker and his collaborators provided the first proof-of-principle for the inflammation hypothesis of atherothrombosis in humans, the first Food and Drug Administration-approved diagnostic test for vascular inflammation (high-sensitivity C-reactive protein) and the first proven anti-inflammatory treatment for heart disease. He is also known internationally for his leadership of more than 15 major multi-national randomised clinical trials, including PREVENT, JUPITER, SPIRE, CANTOS, CIRT, PROMINENT and ZEUS. The recipient of multiple honorary degrees and international awards, Dr Ridker is a Distinguished Scientist of the American Heart Association and an elected member of the National Academy of Sciences, USA. In 2020, in response to the COVID-19 pandemic, he was asked by the US government and the National Heart Lung and Blood Institute to lead the ACTIV-4B Outpatient COVID-19 Thrombosis Prevention Trial.
Dr Ridker earned his medical degree at Harvard Medical School in 1985, and his MPH degree at Harvard School of Public Health in 1990.
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Nikolaus Marx
University Hospital Aachen, Aachen, Germany
Nikolaus Marx is Professor of Medicine / Cardiology and Head of the Department of Internal Medicine I, University Hospital Aachen, Germany. He received his medical training at the Universities of Mainz (Germany), Genf (Switzerland) and Düsseldorf (Germany), obtaining his MD in 1994. His thesis on growth regulation in human renal cancer cell lines was completed at the laboratory of Professor Gerharz at the Institute of Pathology, University of Mainz. After a post-doctoral fellowship with Dr Peter Libby and Dr Jorge Plutzky at Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA, Professor Marx later became a board-certified internist, then cardiologist, before specialising in intensive care medicine in internal medicine at the University of Ulm, Germany. He was appointed Professor of Medicine / Cardiology and Head of the Department of Internal Medicine I at the University of Aachen in 2009.
Professor Marx is a member of several organisations within the field of cardiology and diabetes, including the European Society of Cardiology, the American Heart Association, the German Diabetes Association and the European Association for the Study of Diabetes (EASD). In addition to reviewing submitted manuscripts to numerous journals, including Circulation, Diabetologia, Diabetes, Diabetes Care, Journal of Immunology and The Lancet, he is currently Associate Editor for European Heart Journal. Professor Marx was awarded the Servier Young Investigators Award in 1999 at the First European Meeting on Vascular Biology and Medicine, the 2004 Morgagni Young Investigator Award, as well as the Rising Star Award 2005 of the EASD. Professor Marx served as President of the German Atherosclerosis Society (DGAF) from 2012 to 2015, and was a board member of the German Society of Cardiology (DGK) from May 2017 to April 2019.
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